Fig. 1 · Structure

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20-5,14-HEDE

20-HETE Mimetic

20-5,14-HEDE is a synthetic analog of 20-HETE that primarily targets the PI3K/Akt signaling pathway. This compound exhibits significant anti-apoptotic properties and promotes cell survival, making it valuable for studies related to cellular resilience. Additionally, 20-5,14-HEDE functions as an agonist for 20-HETE, increasing intracellular calcium levels and enhancing vasoconstriction. Its multifaceted biological activities make it suitable for research in cardiovascular and cellular signaling pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 240427-86-5
Applications 20-HETE Mimetic
Formula C20H36O3
Molecular Weight 324.50
Synonyms WIT003
SMILES
OCCCCC/C=C\CCCCCCC/C=C\CCCC(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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