Fig. 1 · Structure

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20-5,14-HEDGE

20-HETE Analog

20-5,14-HEDGE is a 20-HETE analog that targets various cellular pathways to induce apoptosis. It has been shown to promote reactive oxygen species (ROS) production and mitigate hypoxia-reoxygenation-induced cell death in organotypic hippocampal slice cultures and ex vivo rat lung slices. Additionally, 20-5,14-HEDGE provides protection against lung ischemic reperfusion injury in rodent models. This compound is particularly valuable for investigations into pulmonary vascular signaling and mechanisms related to lung injury.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1092380-14-7
Applications 20-HETE Analog
Formula C22H39NO4
Molecular Weight 381.55
SMILES
OC(CNC(CCC/C=C\CCCCCCC/C=C\CCCCCO)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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