Fig. 1 · Structure
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20α-Dihydroprogesterone
Aromatase Inhibitor
20α-Dihydroprogesterone is a potent inhibitor of the aromatase enzyme. It effectively reduces cell proliferation and migration in breast tissue, demonstrating significant biological activity. In the MCF-7aro cell line, 20α-Dihydroprogesterone exhibits an IC50 of approximately 5 μM, making it a valuable tool for research in estrogen-related pathways and cancer biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 145-14-2 |
| Applications | Aromatase Inhibitor |
| Formula | C21H32O2 |
| Molecular Weight | 316.48 |
| Synonyms | 20-OH-P |
| SMILES | C[C@@]12[C@]3([H])[C@](CCC1=CC(CC2)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@@H](O)C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.