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20β-Dihydrocortisol

Catalog No.: A64698
Metabolite of Hydrocortisone
20β-Dihydrocortisol is a metabolite of Hydrocortisone that acts as a weak endogenous agonist of the glucocorticoid receptor (GR). This compound is generated from Hydrocortisone through the action of carbonyl reductase 1 (CBR1) in an NADPH-dependent process. Its unique properties make 20β-Dihydrocortisol valuable for investigating metabolic disorders such as obesity and its impact on glucocorticoid signaling pathways.
20β-Dihydrocortisol 116-58-5 Metabolite of Hydrocortisone
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Size Price Stock Qty
5mg
$125.00
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10mg
$210.00
In stock
25mg
$405.00
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description20β-Dihydrocortisol is a metabolite of Hydrocortisone that acts as a weak endogenous agonist of the glucocorticoid receptor (GR). This compound is generated from Hydrocortisone through the action of carbonyl reductase 1 (CBR1) in an NADPH-dependent process. Its unique properties make 20β-Dihydrocortisol valuable for investigating metabolic disorders such as obesity and its impact on glucocorticoid signaling pathways.
Product Information
Catalog NumA64698
FormulaC21H32O5
Molecular Weight364.48
CAS Number116-58-5
SMILESO=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@@]4([C@H](O)CO)O)=C1
Synonyms20β-DHF
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Endocrinology-Hormones > Glucocorticoid receptors