Fig. 1 · Structure

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21-Hydroxyisoohchininolide

Anticancer Agent

21-Hydroxyisoohchininolide is a salannin-type limonoid that acts as an anticancer agent. It effectively inhibits lipopolysaccharide-induced nitric oxide production in mouse macrophages, demonstrating its ability to modulate inflammatory responses. Additionally, 21-Hydroxyisoohchininolide exhibits cytotoxic activity against leukemia and breast cancer cells, making it valuable for cancer research. Its further application includes the suppression of phorbol 12-myristate 13-acetate-induced activation of Epstein-Barr virus early antigen in lymphocytes, highlighting its potential in studying both cancer and inflammatory diseases.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1429747-14-7
Applications Anticancer Agent
Formula C36H42O10
Molecular Weight 634.71
SMILES
C[C@]12[C@@]3([H])[C@](OC[C@@]3([C@@H](C[C@@H]2OC(/C=C/C4=CC=CC=C4)=O)O)C)([H])[C@]5([H])[C@]([C@@H]1CC(OC)=O)(C6=C(C)[C@H](C7=CC(OC7O)=O)C[C@@]6([H])O5)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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