Fig. 1 · Structure
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21-Hydroxyoligomycin A
K-Ras PM Localization Inhibitor
21-Hydroxyoligomycin A is a potent inhibitor of K-Ras plasma membrane localization, exhibiting an IC50 value of 4.82 nM. This compound demonstrates cytotoxic effects and is derived from the bacterium Streptomyces. It is useful for studying K-Ras signaling pathways and their implications in cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 102042-09-1 |
| Applications | K-Ras PM Localization Inhibitor |
| Formula | C45H74O12 |
| Molecular Weight | 807.06 |
| SMILES | C[C@@H]([C@]1([H])OC(/C=C/[C@@H]([C@H]([C@@H](C([C@@H]([C@H]([C@@H]2C)O)C)=O)C)O)C)=O)[C@@](O[C@H]3C[C@H](O)C)(CC[C@@H]3C)O[C@](C[C@H]([C@H](/C=C/C=C\C[C@H]([C@@H]([C@@](O)(C2=O)C)O)C)CC)O)([H])[C@H]1C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.