Fig. 1 · Structure
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24,25-Epoxycholesterol
LXR Agonists
24,25-Epoxycholesterol is an oxysterol that acts as an agonist of the liver X receptor (LXR). This compound has been shown to inhibit the activity of 3-hydroxy-3-methylglutaryl-CoA reductase (HMG-CoA reductase) in liver cells, thereby playing a crucial role in the regulation of cholesterol metabolism. It is a valuable tool for research applications related to lipid metabolism and cardiovascular health.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 72542-49-5 |
| Applications | LXR Agonists |
| Formula | C27H44O2 |
| Molecular Weight | 400.64 |
| SMILES | C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC3C(C)(O3)C)([H])[C@@]4([H])[C@@](CC1)([H])[C@@]5(C(C[C@H](CC5)O)=CC4)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.