Fig. 1 · Structure
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24-Methylenecholesterol
Sterol
24-Methylenecholesterol is a sterol that primarily targets acyl-CoA cholesterol acyltransferase (ACAT). It exhibits significant anti-aging and neuroprotective properties, mimicking the effects of nerve growth factor (NGF). Key biological activities include extending yeast lifespan through oxidative stress mitigation and displaying neuroprotective effects in PC12 cells. This compound effectively reduces intracellular reactive oxygen species (ROS) and malondialdehyde (MDA) levels while activating antioxidative stress pathways and promoting synaptic growth, making it a valuable tool for research in aging and neurobiology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 474-63-5 |
| Applications | Sterol |
| Formula | C28H46O |
| Molecular Weight | 398.66 |
| Synonyms | Ostreasterol |
| SMILES | C=C(C(C)C)CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.