Fig. 1 · Structure

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24-Norursodeoxycholic acid

24-norursodeoxycholic acid (norUDCA) is a side chain-shortened C23 homologue of UDCA and has shown potent anti-cholestatic, anti-inflammatory and anti-fibrotic properties.

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Biological Activity

Cellular Effect

Cell Line Activity Value Description Reference
CHO EC50 47.2 μM Agonist activity at human TGR5 expressed in CHO cells by luciferase assay [PMID: 18307294]

Specifications

Manufacturer Adooq Bioscience
CAS Number 99697-24-2
Formula C23H38O4
Molecular Weight 378.55
Synonyms nor-UDCA
SMILES
C[C@H](CC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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