Fig. 1 · Structure
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25(S)-27-Hydroxy cholesterol
LXR Activator
25(S)-27-Hydroxy cholesterol is an LXR (liver X receptor) activator derived from CYP27A1-mediated cholesterol hydroxylation. This compound is known to inhibit the proliferation of melanoma cells, making it a valuable reagent for studies investigating cholesterol metabolism and its role in cancer biology. Additionally, its modulation of LXR activity presents opportunities for research into metabolic disorders and related therapeutic avenues.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 56845-83-1 |
| Applications | LXR Activator |
| Formula | C27H46O2 |
| Molecular Weight | 402.65 |
| SMILES | C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC[C@H](C)CO)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=CC3)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.