Fig. 1 · Structure
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25I-NBF hydrochloride
5-HT Receptor Agonist
25I-NBF hydrochloride is a potent partial agonist of the 5-HT2A receptor, exhibiting a Ki value of 0.26 nM and an EC50 of 1.6 nM. This compound is primarily utilized in neuropharmacological research to investigate the role of 5-HT2A receptor modulation in various physiological and pathological processes. Its potency and selectivity make it a valuable tool for studying serotonergic signaling pathways and the development of related therapeutic agents.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Partial Agonist |
| CAS Number | 1539266-13-1 |
| Applications | 5-HT Receptor Agonist |
| Formula | C17H20ClFINO2 |
| Molecular Weight | 451.70 |
| SMILES | COC1=C(I)C=C(OC)C(CCNCC2=CC=CC=C2F)=C1.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.