Fig. 1 · Structure
Documents & Downloads
27-Hydroxycholesterol
LXR Agonist
27-Hydroxycholesterol (27-OHC) is an agonist of the liver X receptor (LXR), a key regulator in cholesterol metabolism and homeostasis. This compound exhibits significant biological activity in lipid regulation and inflammation modulation. 27-OHC is utilized in research applications focused on atherogenesis, cardiovascular disease, and metabolic disorders, providing insights into the role of LXR in disease progression and therapeutic potential.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 20380-11-4 |
| Applications | LXR Agonist |
| Formula | C27H46O2 |
| Molecular Weight | 402.65 |
| Synonyms | 27-OHC |
| SMILES | C[C@@H](CO)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.