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(2R,3S)-Emricasan

Emricasan Lsomer

(2R,3S)-Emricasan is an isomer of Emricasan that functions as an irreversible pan-caspase inhibitor. By inhibiting caspase-3 activity, it effectively mitigates Zika virus (ZIKV)-induced cytotoxicity in human cortical neural progenitors. This compound serves as a valuable tool in neurovirology and apoptosis research, allowing for the exploration of caspase pathways and their implications in viral infections and neurodegenerative diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	409369-54-6
Applications	Emricasan Lsomer
Formula	C₂₆H₂₇F₄N₃O₇
Molecular Weight	569.50
Synonyms	(2R,3S)-PF 03491390; (2R,3S)-IDN-6556
SMILES	FC1=C(C(F)=C(C=C1F)F)OCC([C@@H](NC([C@H](NC(C(NC2=C(C=CC=C2)C(C)(C)C)=O)=O)C)=O)CC(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.