Fig. 1 · Structure
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(2R,4R)-APDC
Group II mGluRs Agonist
(2R,4R)-APDC is an agonist of the group II metabotropic glutamate receptors (mGluRs). It modulates cell proliferation by inhibiting glutamate release, enhancing motor responses linked to D1 receptor activation, and lowering levels of brain-derived neurotrophic factor (BDNF). This compound is valuable for investigating epilepsy and other neurological disorders, providing insights into glutamatergic signaling and its impact on neurobiology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 169209-63-6 |
| Applications | Group II mGluRs Agonist |
| Formula | C6H10N2O4 |
| Molecular Weight | 174.15 |
| Synonyms | (2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylic acid |
| SMILES | O=C([C@@H]1NC[C@](C(O)=O)(N)C1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.