Fig. 1 · Structure
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(2R/S)-6-PNG
Cav3.2 T-channels Blocker
(2R/S)-6-PNG is a selective blocker of Cav3.2 T-type calcium channels, exhibiting potent and reversible inhibitory effects. This compound effectively penetrates the blood-brain barrier, making it valuable for neurological studies. Research has demonstrated its capability to suppress neuropathic and visceral pain in murine models, highlighting its potential applications in pain management and neuropharmacology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Blocker |
| CAS Number | 68682-01-9 |
| Applications | Cav3.2 T-channels Blocker |
| Formula | C20H20O5 |
| Molecular Weight | 340.37 |
| Synonyms | 6-Prenylnaringenin; (±)-6-Prenylnaringenin |
| SMILES | O=C1CC(C2=CC=C(O)C=C2)OC3=CC(O)=C(C/C=C(C)\C)C(O)=C13 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.