Fig. 1 · Structure
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(2S,3R)-Voruciclib hydrochloride
CDK Inhibitor
(2S,3R)-Voruciclib hydrochloride is a selective inhibitor of cyclin-dependent kinases (CDKs), demonstrating potent activity against various CDK isoforms. This compound is primarily used in the study of cell cycle regulation and cancer biology, providing insights into mechanisms of proliferation and tumor growth. Its oral bioavailability makes it a valuable tool for in vivo research applications in cancer therapeutics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2920469-94-7 |
| Applications | CDK Inhibitor |
| Formula | C22H20Cl2F3NO5 |
| Molecular Weight | 506.30 |
| SMILES | Cl[H].ClC1=CC(C(F)(F)F)=CC=C1C(OC2=C(C(O)=CC(O)=C23)[C@H]([C@H]4CO)CCN4C)=CC3=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.