Fig. 1 · Structure
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3,4,5-Trimethoxycinnamic acid
GABA Receptor Agonist
3,4,5-Trimethoxycinnamic acid is a phenylpropanoid known to act as a GABA receptor agonist. This compound has demonstrated anti-stress effects and is capable of prolonging sleep duration in animal models. Furthermore, 3,4,5-Trimethoxycinnamic acid increases the expression of GAD65 and the γ-subunit of the GABAA receptor, with no significant impact on the levels of α- and β-subunits. This makes it a valuable reagent for research into sleep regulation and stress response mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 90-50-6 |
| Applications | GABA Receptor Agonist |
| Formula | C12H14O5 |
| Molecular Weight | 238.24 |
| SMILES | COC1=C(OC)C(OC)=CC(/C=C/C(O)=O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.