Fig. 1 · Structure

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3',4'-Anhydrovinblastine

Cat. No. A14781 CAS 38390-45-3
3',4'-Anhydrovinblastine, extracted from Catharanthus roseus (L.)G.Don.

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Biological Activity

Cellular Effect

Cell Line Activity Value Description Reference
HepG2 IC50 4.53 μM Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay [PMID: 26522953]
KB IC50 2.06 μM Cytotoxicity against human KB cells after 72 hrs by SRB assay [PMID: 26522953]
Lu1 IC50 5.98 μM Cytotoxicity against human Lu1 cells after 72 hrs by SRB assay [PMID: 26522953]
MCF7 IC50 4.63 μM Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay [PMID: 26522953]

Specifications

Manufacturer Adooq Bioscience
CAS Number 38390-45-3
Formula C46H56N4O8
Molecular Weight 792.96
Synonyms 3',4'-Dehydroisoleurosine
SMILES
CCC1=CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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