3-(4-Bromo-2-chlorophenyl)piperidine-2,6-dione is a ligand for the CRBN-type E3 ubiquitin ligase, facilitating targeted protein degradation via the PROTAC (proteolysis-targeting chimeras) approach. This compound can be employed in the development of novel therapeutics that harness the ubiquitin-proteasome system for selective removal of specific proteins. Its applications are significant in disease models where modulation of protein levels is desired for research and therapeutic purposes.
3-(4-Bromo-2-chlorophenyl)piperidine-2,6-dione is a ligand for the CRBN-type E3 ubiquitin ligase, facilitating targeted protein degradation via the PROTAC (proteolysis-targeting chimeras) approach. This compound can be employed in the development of novel therapeutics that harness the ubiquitin-proteasome system for selective removal of specific proteins. Its applications are significant in disease models where modulation of protein levels is desired for research and therapeutic purposes.
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