3,4-DAA is an orally active anthranilic acid derivative that acts as an immunosuppressive agent. It effectively mitigates colitis severity by inhibiting Th1 cell responses and promoting the expression of Th2 cytokines, as well as inducing CD4+CD25+ T cell expression. Additionally, 3,4-DAA reduces the expression of inducible nitric oxide synthase (iNOS) and the release of nitric oxide (NO) from EOC20 cells stimulated by IFN-γ and lipopolysaccharide. This makes it a valuable tool for research in immunology and inflammatory diseases.
3,4-DAA is an orally active anthranilic acid derivative that acts as an immunosuppressive agent. It effectively mitigates colitis severity by inhibiting Th1 cell responses and promoting the expression of Th2 cytokines, as well as inducing CD4+CD25+ T cell expression. Additionally, 3,4-DAA reduces the expression of inducible nitric oxide synthase (iNOS) and the release of nitric oxide (NO) from EOC20 cells stimulated by IFN-γ and lipopolysaccharide. This makes it a valuable tool for research in immunology and inflammatory diseases.
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