Fig. 1 · Structure
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3-(7-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione
Lenalidomide Analog
3-(7-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione is a Lenalidomide analog targeting the ubiquitin-proteasome system. This compound exhibits notable biological activity in the development of PROTACs (proteolysis-targeting chimeras), providing a valuable tool for research into targeted protein degradation. Its structural features enhance the potential for therapeutic applications in oncology and related fields.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 2229976-08-1 |
| Applications | Lenalidomide Analog |
| Formula | C13H11BrN2O3 |
| Molecular Weight | 323.15 |
| SMILES | O=C(C(N(CC1=C2C(Br)=CC=C1)C2=O)CC3)NC3=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.