Fig. 1 · Structure
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3,7-DMF
HSCs Inhibitor
3,7-DMF is an orally active inhibitor targeting the activation of hepatic stellate cells (HSCs) induced by TGF-β1. This compound promotes the expression of antioxidant genes and effectively reduces reactive oxygen species (ROS) levels. It is a valuable tool for studying mechanisms of liver fibrosis and elucidating potential therapeutic strategies for hepatic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 20950-52-1 |
| Applications | HSCs Inhibitor |
| Formula | C17H14O4 |
| Molecular Weight | 282.29 |
| SMILES | O=C1C(OC)=C(C2=CC=CC=C2)OC3=C1C=CC(OC)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.