Fig. 1 · Structure

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3′-Amino-2′,3′-dideoxy-GTP

GTP Derivative

3′-Amino-2′,3′-dideoxy-GTP is a GTP derivative that functions as a chain terminator in DNA synthesis. This reagent is essential for studies involving nucleotide incorporation and nucleotide analogs, aiding in the investigation of DNA replication and transcription processes. Its application extends to the development of antiviral and anticancer therapeutics by providing insights into the mechanisms of action of nucleoside analogs.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 90053-19-3
Applications GTP Derivative
Formula C10H17N6O12P3
Molecular Weight 506.20
SMILES
O=P(OP(OP(O)(O)=O)(O)=O)(O)OC[C@H]1O[C@@H](N2C(NC(N)=NC3=O)=C3N=C2)C[C@@H]1N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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