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3'-Amino-2',3'-dideoxy-TTP

TTP Derivative

3'-Amino-2',3'-dideoxy-TTP is a thymidine triphosphate (TTP) derivative designed to function as a chain terminator in DNA synthesis. Its incorporation into DNA strands halts further elongation, making it a valuable reagent for applications in molecular biology, such as site-directed mutagenesis and the study of DNA polymerase activities. This compound aids in elucidating the mechanisms of DNA replication and can be instrumental in developing diagnostic assays or therapeutic strategies targeting nucleic acid synthesis.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	90053-16-0
Applications	TTP Derivative
Formula	C₁₀H₁₈N₃O₁₃P₃
Molecular Weight	481.18
SMILES	O=P(OP(OP(O)(O)=O)(O)=O)(O)OC[C@H]1O[C@@H](N2C(NC(C(C)=C2)=O)=O)C[C@@H]1N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.