Fig. 1 · Structure
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3-Amino-4,6-dimethylpyridine
UHRF1 Inhibitor
3-Amino-4,6-dimethylpyridine is a potent UHRF1 inhibitor, specifically targeting the Arg-binding cavity within the UHRF1 TTD domain. This compound effectively disrupts the interaction between UHRF1 and LIG1, thereby interfering with DNA methylation processes. It has valuable applications in cancer research, facilitating the investigation of epigenetic regulation and potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1193-71-1 |
| Applications | UHRF1 Inhibitor |
| Formula | C7H10N2 |
| Molecular Weight | 122.17 |
| Synonyms | 5A-DMP |
| SMILES | CC1=CC(C)=NC=C1N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.