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3-Azathalidomide

Thalidomide Analog

3-Azathalidomide is a Thalidomide analog that primarily targets the E3 ubiquitin ligase, making it a valuable tool in protein degradation studies. This compound exhibits biological activity that facilitates the development of PROTACs (proteolysis-targeting chimeras), enabling targeted protein degradation in various cellular contexts. Its application is particularly relevant in drug discovery and targeted therapeutics research, where modulation of protein levels is essential for understanding disease mechanisms and therapeutic interventions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	31804-66-7
Applications	Thalidomide Analog
Formula	C₁₂H₉N₃O₄
Molecular Weight	259.22
SMILES	O=C1N(C(CC2)C(NC2=O)=O)C(C3=NC=CC=C31)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.