Fig. 1 · Structure

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3'-DMTr-dA

Oligonucleotide

3'-DMTr-dA is a protected deoxyadenosine nucleotide primarily used in oligonucleotide synthesis. Its 3'-dimethoxytrityl (DMTr) group serves as a protective moiety, allowing for selective phosphorylation and coupling during solid-phase synthesis. This compound is essential for the preparation of DNA probes, primers, and therapeutic oligonucleotides in molecular biology research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 140712-82-9
Applications Oligonucleotide
Formula C47H52N7O7P
Molecular Weight 857.93
SMILES
CC(C)N(C(C)C)P(OCCC#N)OC[C@@H]1[C@@H](OC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)C[C@H](N5C=NC6=C5N=CN=C6NC(C7=CC=CC=C7)=O)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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