3-Fluoro-desmethyl-cabozantinib

Catalog No.: A34350
Target Protein Ligand
3-Fluoro-desmethyl-cabozantinib is a selective ligand for the BCL6 protein, facilitating targeted protein degradation through PROTAC technology. It serves as an essential building block in the development of innovative therapeutics aimed at modulating protein levels for various cancer applications. This compound may enhance research into BCL6-related pathways and assist in the design of more effective treatments.
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Size Stock
5mg
10mg
50mg
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description3-Fluoro-desmethyl-cabozantinib is a selective ligand for the BCL6 protein, facilitating targeted protein degradation through PROTAC technology. It serves as an essential building block in the development of innovative therapeutics aimed at modulating protein levels for various cancer applications. This compound may enhance research into BCL6-related pathways and assist in the design of more effective treatments.
Product Information
Catalog NumA34350
FormulaC27H21F2N3O5
Molecular Weight505.47
CAS Number849217-50-1
SMILESO=C(C1(CC1)C(NC2=CC=C(C(F)=C2)OC3=C4C=C(OC)C(O)=CC4=NC=C3)=O)NC5=CC=C(C=C5)F
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