Fig. 1 · Structure
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3-Hydroxy desloratadine
Metabolite
3-Hydroxy desloratadine is a metabolic derivative of Desloratadine, primarily functioning as an antihistamine. It exhibits biological activity by antagonizing H1 receptors, thereby reducing allergic reactions and inflammation. This compound is utilized in pharmacokinetic studies and metabolic profiling related to antihistamine efficacy and safety assessments.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 119410-08-1 |
| Applications | Metabolite |
| Formula | C19H19ClN2O |
| Molecular Weight | 326.82 |
| SMILES | OC1=CC2=C(/C(C3=C(CC2)C=C(Cl)C=C3)=C4CCNCC\4)N=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.