Fig. 1 · Structure
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3-Hydroxybutyrate dehydrogenase
Mitochondrial Enzyme
3-Hydroxybutyrate dehydrogenase is a mitochondrial enzyme essential for both the synthesis and degradation of ketone bodies, playing a pivotal role in energy metabolism. It facilitates the conversion of 3-hydroxybutyrate to acetoacetate, a critical step in the utilization of fatty acids during periods of fasting. Dysregulation or deficiency of 3-Hydroxybutyrate dehydrogenase can impede fatty acid oxidation in the liver, leading to lipid accumulation and potentially contributing to the development of fatty liver disease. This enzyme is valuable for research on metabolic disorders and energy homeostasis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 9028-38-0 |
| Applications | Mitochondrial Enzyme |
| Synonyms | 3-HBDH |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.