Fig. 1 · Structure
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3-Hydroxykynurenine
Endogenous Neurotoxin
3-Hydroxykynurenine, a tryptophan metabolite, functions as a potential endogenous neurotoxin. Elevated levels of this compound have been associated with various neurodegenerative disorders, highlighting its role in neurotoxicity. Research indicates that 3-Hydroxykynurenine can induce neuronal apoptosis, making it a valuable tool for studying neurodegenerative mechanisms and therapeutic targets.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 484-78-6 |
| Applications | Endogenous Neurotoxin |
| Formula | C10H12N2O4 |
| Molecular Weight | 224.21 |
| Synonyms | 3-Hydroxy-DL-kynurenine |
| SMILES | O=C(O)C(N)CC(C1=CC=CC(O)=C1N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.