Fig. 1 · Structure
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3-IN-PP1
PKD Inhibitor
3-IN-PP1 is a selective inhibitor of protein kinase D (PKD), demonstrating potent inhibition across PKD isoforms PKD1, PKD2, and PKD3 with IC50 values of 108 nM, 94 nM, and 108 nM, respectively. This compound exhibits broad-spectrum anticancer activity, effectively inhibiting the proliferation of various tumor cell lines. 3-IN-PP1 serves as a valuable tool for cancer research, particularly in studying the role of PKD signaling pathways in tumor growth and development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2227110-54-3 |
| Applications | PKD Inhibitor |
| Formula | C17H18N6 |
| Molecular Weight | 306.37 |
| SMILES | NC1=C2C(N(C(C)(C)C)N=C2C3=CNC4=C3C=CC=C4)=NC=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.