Fig. 1 · Structure
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3-Methyl-2-nitrophenol
UDP-glucuronyltransferase Acceptor Substrate
3-Methyl-2-nitrophenol is a specific acceptor substrate for UDP-glucuronyltransferase (EC 2.4.1.17), facilitating the enzymatic process of glucuronidation to generate a glucuronide conjugate. This compound is characterized by its enhanced lipid solubility, which increases the conversion rate during glucuronidation. Additionally, 3-Methyl-2-nitrophenol displays reduced absorbance at 340 nm, making it a suitable substrate for the NADH-NAD+-linked UDP-glucuronyltransferase assay with minimal interference. This reagent is valuable in studies related to drug metabolism and pharmacokinetics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 4920-77-8 |
| Applications | UDP-glucuronyltransferase Acceptor Substrate |
| Formula | C7H7NO3 |
| Molecular Weight | 153.14 |
| SMILES | O=N(=O)C=1C(O)=CC=CC1C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.