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3-Methylglutaric acid-d4

稳定同位素

3-Methylglutaric acid-d4 is a deuterium-labeled derivative of 3-Methylglutaric acid, functioning as a non-selective inhibitor of mitochondrial activity and Na+, K+-ATPase, exhibiting a 30% inhibition rate in rat cortical synaptosomal preparations. This compound promotes the generation of reactive oxygen species (ROS), leading to oxidative damage and reduced mitochondrial redox potential, as well as impairing ion pump functionality in cell membranes. 3-Methylglutaric acid-d4 is valuable for investigating the neuropathological mechanisms associated with metabolic disorders and the impact of oxidative stress on neuronal damage in neurodegenerative research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1219798-68-1
Applications	稳定同位素
Formula	C₆H₆D₄O₄
Molecular Weight	150.17
SMILES	OC(C([2H])([2H])C(C)C([2H])([2H])C(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.