Fig. 1 · Structure
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3-Methylguanine
Alkylated DNA
3-Methylguanine is a DNA modification resulting from alkylation, primarily targeting guanine residues. This compound is known for its cytotoxic effects, leading to cell death through the inhibition of DNA replication. 3-Methylguanine serves as a valuable tool in research focused on elucidating mechanisms of DNA damage induced by alkylating agents and exploring the corresponding repair pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2958-98-7 |
| Applications | Alkylated DNA |
| Formula | C6H7N5O |
| Molecular Weight | 165.15 |
| Synonyms | 3-MG |
| SMILES | O=C1N=C(N(C)C2=C1NC=N2)N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.