Fig. 1 · Structure
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3-Nitrophenyl disulfide
M1PDH Inhibitor
3-Nitrophenyl disulfide is a selective inhibitor of mannitol-1-phosphate dehydrogenase (M1PDH), exhibiting an IC50 of 3 μM. This compound demonstrates significant antiparasitic activity, making it valuable for studies aimed at elucidating metabolic pathways in parasitic organisms. Its role as an M1PDH inhibitor provides a unique tool for research into potential therapeutic applications targeting parasitic diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 537-91-7 |
| Applications | M1PDH Inhibitor |
| Formula | C12H8N2O4S2 |
| Molecular Weight | 308.33 |
| Synonyms | Bis(3-nitrophenyl) disulfide; Nitrophenide |
| SMILES | O=[N+](C1=CC(SSC2=CC=CC([N+]([O-])=O)=C2)=CC=C1)[O-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.