Fig. 1 · Structure

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3-O-Methyldopa-d3

Stable Isotope

3-O-Methyldopa-d3 is a deuterium-labeled analog of 3-O-Methyldopa, a metabolite of L-DOPA that effectively crosses the blood-brain barrier. This compound plays a significant role in inhibiting the astrocyte-mediated neuroprotective effects of L-DOPA on dopaminergic neurons while also exhibiting antidepressant and neuroprotective properties. Its unique isotopic labeling allows for advanced research into nervous system disorders, including depression and Parkinson's disease.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 586954-09-8
Applications Stable Isotope
Formula C10H10D3NO4
Molecular Weight 214.23
Synonyms 3-Methoxy-L-tyrosine-d3; 3-O-Methyl-L-DOPA-d3
SMILES
N[C@@H](CC1=CC=C(O)C(OC([2H])([2H])[2H])=C1)C(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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