Fig. 1 · Structure
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3'-O-Methyltaxifolin
Anticancer Agents
3'-O-Methyltaxifolin, also known as (+)-Dihydroisorhamnetin, is a dihydroflavanol derived from Pulicaria jaubertii. This compound demonstrates significant anticancer activity, exhibiting IC50 values of 19.1 μg against prostate cancer (PC-3), 20.0 μg against breast cancer (MCF-7), and 24.1 μg against hepatocellular carcinoma (HepG-2) cell lines. Additionally, 3'-O-Methyltaxifolin has been shown to induce apoptosis in cancer cells, positioning it as a promising candidate for further research in cancer therapeutics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 55812-91-4 |
| Applications | Anticancer Agents |
| Formula | C16H14O7 |
| Molecular Weight | 318.28 |
| Synonyms | (+)-Dihydroisorhamnetin |
| SMILES | O=C1C2=C(O)C=C(O)C=C2O[C@H](C3=CC(OC)=C(C=C3)O)[C@H]1O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.