3-OH-Kynurenamine is an aryl hydrocarbon receptor (AhR) activator that modulates immune responses. This compound enhances the expression of immune regulatory genes such as Ido1 and Tgfb1, demonstrating therapeutic potential in reducing skin inflammation in psoriasis mouse models, as well as alleviating kidney damage in nephrotoxic lupus mouse models. Its unique biological activity makes it valuable for research involving immune modulation and inflammatory diseases.
3-OH-Kynurenamine is an aryl hydrocarbon receptor (AhR) activator that modulates immune responses. This compound enhances the expression of immune regulatory genes such as Ido1 and Tgfb1, demonstrating therapeutic potential in reducing skin inflammation in psoriasis mouse models, as well as alleviating kidney damage in nephrotoxic lupus mouse models. Its unique biological activity makes it valuable for research involving immune modulation and inflammatory diseases.
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