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3A-MPLA ammonium

Catalog No.: A35389
TLR-4 Agonist
3A-MPLA ammonium is a monophosphoryl rri-acyl lipid A that acts as a Toll-like receptor 4 (TLR-4) agonist. It is known to stimulate immune responses by activating the TLR-4 pathway, leading to the production of pro-inflammatory cytokines. This compound is valuable in research applications focused on immunology, vaccine development, and the study of host-pathogen interactions.
3A-MPLA ammonium 1699735-80-2 TLR-4 Agonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description3A-MPLA ammonium is a monophosphoryl rri-acyl lipid A that acts as a Toll-like receptor 4 (TLR-4) agonist. It is known to stimulate immune responses by activating the TLR-4 pathway, leading to the production of pro-inflammatory cytokines. This compound is valuable in research applications focused on immunology, vaccine development, and the study of host-pathogen interactions.
Product Information
Catalog NumA35389
FormulaC54H106N3O17P
Molecular Weight1100.40
CAS Number1699735-80-2
SMILESOC[C@H]1O[C@@H](OC[C@H]2O[C@@H]([C@@H]([C@H]([C@@H]2O)O)NC(C[C@@H](CCCCCCCCCCC)O)=O)O)[C@H](NC(C[C@H](OC(CCCCCCCCCCCCC)=O)CCCCCCCCCCC)=O)[C@@H](O)[C@@H]1OP(O)(O)=O.N
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Immunology & Inflammation > Toll-like Receptors