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3D-Monophosphoryl Lipid (12,16) free acid

Catalog No.: A35417
TLR4 Agonist
3D-Monophosphoryl Lipid (12,16) free acid is a TLR4 agonist that stimulates the immune response through Toll-like receptor 4 activation. This compound serves as a potent vaccine adjuvant, enhancing the immunogenicity of various vaccine formulations. Its application in research includes the development of improved vaccines and studies of innate immune signaling pathways.
3D-Monophosphoryl Lipid (12,16) free acid 220048-49-7 TLR4 Agonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description3D-Monophosphoryl Lipid (12,16) free acid is a TLR4 agonist that stimulates the immune response through Toll-like receptor 4 activation. This compound serves as a potent vaccine adjuvant, enhancing the immunogenicity of various vaccine formulations. Its application in research includes the development of improved vaccines and studies of innate immune signaling pathways.
Product Information
Catalog NumA35417
FormulaC96H181N2O21P
Molecular Weight1730.44
CAS Number220048-49-7
SMILESCCCCCCCCCCCC(O[C@H](CCCCCCCCCCC)CC(N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC[C@@H]2[C@H]([C@@H]([C@H]([C@H](O2)O)NC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCCCCCC)=O)=O)O)O)CO)OP(O)(O)=O)OC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCCCC)=O)=O)=O)=O
Synonyms3D-MPL (12,16) free acid
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Immunology & Inflammation > Toll-like Receptors