((3R,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate) calcium(II)

Catalog No.: A75687
HMG-CoA Reductase (HMGCR) Control
((3R,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate) calcium(II) is a control compound associated with HMG-CoA reductase (HMGCR), a key enzyme involved in cholesterol biosynthesis. This compound serves as an impurity marker in the analysis of Rosuvastatin, an established HMGCR inhibitor. Its role in research applications includes evaluating batch consistency and the purity of statin formulations, facilitating the development and quality control of lipid-lowering therapeutics.
Grouped product items
Size Price Stock Qty
1mg
$210.00
In stock
5mg
$785.00
In stock
10mg
$1,285.00
In stock
25mg
$2,570.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description((3R,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate) calcium(II) is a control compound associated with HMG-CoA reductase (HMGCR), a key enzyme involved in cholesterol biosynthesis. This compound serves as an impurity marker in the analysis of Rosuvastatin, an established HMGCR inhibitor. Its role in research applications includes evaluating batch consistency and the purity of statin formulations, facilitating the development and quality control of lipid-lowering therapeutics.
Product Information
Catalog NumA75687
FormulaC22H28CaFN3O6S
Molecular Weight521.62
CAS Number1422515-55-6
SMILESOC(C[C@H](O)C[C@@H](O)/C=C/C1=C(C(C)C)N=C(N(C)S(C)(=O)=O)N=C1C2=CC=C(C=C2)F)=O.[Ca].[0.5]
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