(3R,5R)-Rosuvastatin Lactone

Catalog No.: B10867
HMG-CoA Inhibitor
(3R,5R)-Rosuvastatin Lactone is an HMG-CoA reductase inhibitor that plays a crucial role in cholesterol biosynthesis modification. This compound exhibits potent lipid-lowering effects, making it valuable for studying dyslipidemia and related cardiovascular diseases. Its applications extend to elucidating mechanisms of action in statin therapies and examining its impact on metabolic pathways.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(3R,5R)-Rosuvastatin Lactone is an HMG-CoA reductase inhibitor that plays a crucial role in cholesterol biosynthesis modification. This compound exhibits potent lipid-lowering effects, making it valuable for studying dyslipidemia and related cardiovascular diseases. Its applications extend to elucidating mechanisms of action in statin therapies and examining its impact on metabolic pathways.
Product Information
Catalog NumB10867
FormulaC22H26FN3O5S
Molecular Weight463.52
CAS Number1422954-11-7
SMILESCS(=O)(N(C1=NC(C(C)C)=C(/C=C/[C@H]2C[C@@H](O)CC(O2)=O)C(C3=CC=C(F)C=C3)=N1)C)=O
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