Fig. 1 · Structure
Documents & Downloads
(3S,5R)-Fluvastatin sodium
HMGCR Inhibitor
(3S,5R)-Fluvastatin sodium is the (3S,5R)-enantiomer of Fluvastatin, a competitive inhibitor of HMG-CoA reductase with an IC50 of 8 nM. This compound demonstrates protective effects on vascular smooth muscle cells by activating the Nrf2-dependent antioxidant pathway, thereby counteracting oxidative stress. It serves as a valuable tool in cardiovascular research and studies focused on cholesterol regulation and metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 94061-81-1 |
| Applications | HMGCR Inhibitor |
| Formula | C24H25FNNaO4 |
| Molecular Weight | 433.45 |
| Synonyms | (3S,5R)-XU 62-320 |
| SMILES | FC1=CC=C(C2=C(/C=C/[C@H](O)C[C@H](O)CC(O[Na])=O)N(C(C)C)C3=C2C=CC=C3)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.