Fig. 1 · Structure
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(3S,5R)-Rosuvastatin-d6 sodium
Stable Isotope
(3S,5R)-Rosuvastatin-d6 sodium is a deuterated form of Rosuvastatin, a potent HMG-CoA reductase inhibitor. This stable isotope is primarily utilized in pharmacokinetic studies and metabolic research to trace and quantify drug metabolism and distribution in biological systems. Its application extends to elucidating the mechanisms of action of statins and understanding lipid-lowering effects in clinical studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2734920-03-5 |
| Applications | Stable Isotope |
| Formula | C22H21D6FN3NaO6S |
| Molecular Weight | 509.56 |
| SMILES | FC1=CC=C(C=C1)C2=NC(N(S(=O)(C)=O)C)=NC(C(C([2H])([2H])[2H])C([2H])([2H])[2H])=C2/C=C/[C@@H](C[C@@H](CC(O[Na])=O)O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.