(3S,6R)-NML is an NMDA receptor antagonist that demonstrates pIC50 values of 4.8 for GluN1-GluN2A, 4.6 for GluN1-GluN2B, and 5.0 for both GluN1-GluN2C and GluN1-GluN2D. This compound is instrumental in studying the role of NMDA receptors in neurological disorders, particularly in depression research. Its specific antagonistic properties make it a valuable tool for investigating synaptic plasticity and related therapeutic approaches.
(3S,6R)-NML is an NMDA receptor antagonist that demonstrates pIC50 values of 4.8 for GluN1-GluN2A, 4.6 for GluN1-GluN2B, and 5.0 for both GluN1-GluN2C and GluN1-GluN2D. This compound is instrumental in studying the role of NMDA receptors in neurological disorders, particularly in depression research. Its specific antagonistic properties make it a valuable tool for investigating synaptic plasticity and related therapeutic approaches.
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