Fig. 1 · Structure
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(3S)Lenalidomide-5-Br
Ligand for E3 Ligase
(3S)Lenalidomide-5-Br is a potent ligand for E3 ubiquitin ligases, facilitating targeted protein degradation through the ubiquitin-proteasome system. This compound is instrumental in research applications involving the development of PROTACs, notably in the synthesis of Cbl-b-IN-1. Its unique structure allows for specific interaction with target proteins, making it a valuable tool in cellular and molecular biology studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 2829898-76-0 |
| Applications | Ligand for E3 Ligase |
| Formula | C13H11BrN2O3 |
| Molecular Weight | 323.15 |
| SMILES | O=C1N([C@@H]2C(NC(CC2)=O)=O)CC3=CC(Br)=CC=C31 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.