Fig. 1 · Structure
Documents & Downloads
4-Acetylsimvastatin
Acetylated Simvastatin
4-Acetylsimvastatin is an acetylated derivative of simvastatin, which acts as a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM. This compound is primarily utilized in research related to lipid metabolism and cholesterol biosynthesis. Its ability to inhibit HMG-CoA reductase makes it significant for studying cardiovascular diseases and the pharmacological effects of statins.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 145576-25-6 |
| Applications | Acetylated Simvastatin |
| Formula | C27H40O6 |
| Molecular Weight | 460.60 |
| SMILES | CCC(C)(C)C(O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](OC(C)=O)CC(O3)=O)[C@@]12[H])=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.