Fig. 1 · Structure
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4-Biphenylsulfonyl chloride
Anticancer Agent
4-Biphenylsulfonyl chloride is a reactive sulfonyl chloride that serves as a synthetic intermediate in the production of sulfonamide derivatives. These derivatives exhibit significant antiproliferative activity against human head and neck squamous cell carcinoma (HNSCC) by enhancing PTEN expression and inhibiting the PI3K/Akt/mTOR signaling pathway. This compound is an important tool in the development of novel anticancer therapeutics targeting HNSCC.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1623-93-4 |
| Applications | Anticancer Agent |
| Formula | C12H9ClO2S |
| Molecular Weight | 252.72 |
| SMILES | ClS(C1=CC=C(C2=CC=CC=C2)C=C1)(=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.