Fig. 1 · Structure
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4-Formylcolchicine
Anticancer Agent
4-Formylcolchicine is a potent anticancer agent that targets tumor cell growth. It exhibits significant cytotoxic activity, demonstrated by IC50 values of 1.007 μM for A549 cells, 0.128 μM for HT-29 cells, and 0.054 μM for HCT116 cells. This compound is valuable for research in cancer biology and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2730-82-7 |
| Applications | Anticancer Agent |
| Formula | C23H25NO7 |
| Molecular Weight | 427.45 |
| SMILES | COC1=C2C(C([C@H](CCC2=C(C(OC)=C1OC)C=O)NC(C)=O)=C3)=CC=C(OC)C3=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.